K. Mukati and L. Bhattacharya, IJGHC, June 2017 – August 2017; Sec. A; Vol.6, No.3, 86-95., DOI: 10.24214/IJGHC/GC/6/3/8695.
The present study was conducted to investigate the safe dose of cadmium chloride on the testis of Heteropneustes fossilis which were kept in aqueous solution of cadmium chloride of 0.5 ppm for 7, 14, and 21 day. The histological changes due to cadmium chloride in testis are characterized by regression after 7 day of exposure. Spermatogonia and spermatocytes in the seminiferous lobule showed degeneration in 14 days duration. Almost all the cells in seminiferous lobules were disintegrate and blurred appearance were visible in after 21 days. The size of all spermatoganic cell significantly (p< 0.001) increased. After the administration of Mulethi alongwith cadmium chloride the degenerated cells exhibited recoupment
Avnish Sharma and Shailendra Jain,IJGHC, June 2017 – August 2017; Sec. A; Vol.6, No.3, 081-085.,DOI: 10.24214/IJGHC/GC/6/3/8185.
Claisen–Schmidt condensation has been carried out for the synthesis of some1-(benzimidazole-2-yl)-3-substituted aryl-2-propene-1-ones is based on microwave assisted solid phase, solvent free protocol. In the present study the condensation has been carried out in presence of base NaOH. The required 2-acetylbenzimidazole was obtained under Philips condition.
Dr. Kishor Kumar Singh,IJGHC, June 2017 – August 2017; Sec. A; Vol.6, No.3, 71-80.,DOI: 10.24214/IJGHC/GC/6/3/7180
An agricultural waste Sugarcane bagasse has been used for the removal of copper (II) from an aqueous solution. The effects of different parameters such as contact time, adsorbate concentration, pH of the medium and temperature were examined. Optimum removal at 200C was found to be 98.6 % at pH 6.6, with an initial Cu (II) concentration of 100 mg L-1. Dynamics of the sorption process and mass transfer of Cu (II) to sorbent were investigated and the values of rate constant of adsorption, rate constant of intraparticle diffusion and the mass transfer coefficients were calculated. Different thermodynamic parameters viz., changes in standard free energy, enthalpy and entropy were evaluated and it was found that the reaction was spontaneous and exothermic in nature. The sorption data fitted the Langmuir isotherm. The data were subjected to multiple regression analysis and a model was developed to predict the removal of Cu (II) from an aqueous solution.
The objective of this study was to investigate the effect of dried leaves and seeds of purslane (Portulace Olerecea) on lipids levels in experimentally induced hypercholesterolemic rats. Thirty six male Albino rats were divided into 6 groups and reared for 1.5 months. The groups were: group (1) control, group (2) fed hypercholesterolemic diet (positive control), group (3) fed 10% grounded seed of Portulace Olerecea, group (4) fed 10% grounded leaves of Portulace Olerecea, group (5) hypercholesterolemic rats fed 10% grounded Portulace Olerecea seeds, group (6) hypercholesterolemic rats fed 10% grounded Portulace Olerecea leaves. At the end of experimental period, all rats were scarified and blood samples were taken for determination of liver function aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) ,and lipid profile( triglyceride TG, cholesterol TC and high density lipoproteins HDL) determination. Also the fecal cholesterol and TG were determined. Liver and heart were taken for pathology analysis. The results showed that liver function activities (ALT, AST and ALP) were significantly decreased in the groups fed on 10% Portulace Olerecea seeds (gp.5) or leaves (gp.6) compared to the hyper-cholesterol group (gp.2). The levels of serum TG, TC were decreased in the group fed on 10% Portulace Olerecea seeds (gp.5) more than the group fed on 10% Portulace Olerecea leaves (gp.6) and both were better than hypercholesteralmic group (gp.2).While the HDL level was increased for both groups of Portulace Olerecea leaves or seeds compared to hypercholestolmic group which decreases in HDL. Fecal TC and TG levels were higher in groups fed 10% Portulace Olerecea leaves (gp.5) or seeds (gp.6) than hypercholesterolmic group (gp.2). Liver and heart histopathology showed more improvement in cell structure in groups fed Portulace Olerecea. The data also revealed that there is an improvement in lipid profile and lipid level discharged in the feces which suggested that Portulace Olerecea seeds reduces lipid in hypercholesteralmic rats and work as hepatoprotective by improving liver function more than leaves compared with high fat group.
C. J. Patil, Manisha C. Patil and Mrunmayee C. Pati
The rare aromatic ketone, 5-Chloro-2-hydroxy-4-methyl-acetophenone condensed with aniline and its six dialkyl derivatives viz. 2,3-Dimethyl-aniline, 2,4-Dimethyl-aniline, 3,4-Dimethyl-aniline, 2,5-Dimethyl-aniline, 2,6-Dimethyl-aniline, and 3,5-Dimethyl-aniline(each separately) efficiently to produced a series of novel ketimines, CJ-0 to CJ-6. These were analyzed by employing the techniques such as thin layer chromatography(TLC) and UV-Vis spectra. All these novel ketimines were characterized by their colour, physical constant, TLC, elemental analysis and spectral(UV-Vis and FTIR) methods. After confirming their desired molecular studies, these novel ketimines were studied for their biological potential.